Osteogenesis Imperfecta (Chow Chow)

Category:

Musculoskeletal - Associated with muscles, bones and associated structures

Gene:

COL1A2

Variant Detected:

c.936+1G>A

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Autosomal Recessive

Recommended Screening:

Genetic testing of the COL1A2 gene will reliably determine if a dog is a genetic carrier of Osteogenesis Imperfecta.

Research Citation(s):

J Hered. 2018 Mar 16;109(3):308-314

Associated Breed(s):

Chow Chow, Mixed Breed,