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Osteochondromatosis - American Staffordshire Terrier Type

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Category:

Musculoskeletal - Associated with muscles, bones and associated structures

Gene:

EXT2

Variant Detected:

C>A

Severity:

Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Friedenberg, S. G., Vansteenkiste, D., Yost, O., Treeful, A. E., Meurs, K. M., Tokarz, D. A., & Olby, N. J. (2018). A de novo mutation in the EXT2 gene associated with osteochondromatosis in a litter of American Staffordshire Terriers. Journal of Veterinary Internal Medicine, 32(3), 986–992.

Associated Breed(s):

American Staffordshire Terrier, Mixed Breed,

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