Laryngeal Paralysis (Bull Terrier Type)

Category:

Nervous system / Neurologic - Associated with the brain, spinal cord and nerves

Gene:

RAPGEF6

Variant Detected:

c.1793_1794ins36, p.(Ile587ProfsTer5) on Chr 11

Severity:

Moderate-Severe. This is a disease with significant welfare impact on the affected animal, in terms of clinical signs and generally reduced life expectancy.

Mode of Inheritance:

Autosomal Recessive with Incomplete Penetrance

Research Citation(s):

Hadji Rasouliha, 2019, PLoS Genet 15(10): e1008416.

Associated Breed(s):

Bull Terrier, Miniature Bull Terrier,