Complement 3 Deficiency

Category:

Immunologic - Associated with the organs and cells of the immune system

Gene:

C3

Variant Detected:

deletion c.2136del/p.(F712Lfs*11) chr20

Severity:

Moderate-Severe. This is a disease with significant welfare impact on the affected animal, in terms of clinical signs and generally reduced life expectancy.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

https://pubmed.ncbi.nlm.nih.gov/3789016/

Associated Breed(s):

Mixed Breed,