Globoid Cell Leukodystrophy (Irish Setter Type)

Category:

Metabolic - Associated with the enzymes and metabolic processes of cells

Gene:

GALC

Variant Detected:

chr8: c.790_791insN[78]

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

https://pubmed.ncbi.nlm.nih.gov/16490723/

Associated Breed(s):

Irish Red and White Setter, Irish Setter,